Pamela Silver is the Elliot T and Onie H Adams Professor of Biochemistry and Systems Biology at Harvard Medical School. She is also a full member of the Wyss Institute of Biologically Inspired Engineering. She was one of the first members of the Department of Systems Biology and the first Director of the Harvard University Graduate Program in Systems Biology.
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Senior Staff Scientist
Jeff’s current research interests are in therapeutic protein development and bioenergy. As a senior staff scientist at the Wyss, he is also supporting faculty-driven efforts in DNA synthesis and DNA assembly. Before coming to the Wyss, he was Director of Structural Biology and Director of Intellectual Property at EMD Serono, a major protein-focused pharmaceutical company, where he designed protein drugs. Previously, he was a Director of Intellectual Property and Director of Communications there. He has published numerous articles on drug development, synthetic biology, nervous system development, and bacterial genetics, and holds several patent applications and issued patents. He received his Ph.D. and B.A from Harvard University.
Roger Larken Chang
Associate Lab DirectorLife Sciences Research Foundation Fellow 2014
Ph.D. Bioinformatics and Systems Biology, UC San Diego
B.A. Molecular and Cell Biology, UC Berkeley
Roger’s current research interests are in the study of proteome-wide oxidative stress resistance, as in the radioresistance of the polyextremophile Deinococcus radiodurans, and in engineering protein therapeutics to induce cryptobiosis (“hidden mode of life”) in mammalian and other eukaryotic cells to preserve cells and tissues and confer diverse environmental stress resistance. Roger previously developed landmark models for structural systems biology of E. coli metabolism to identify growth-limiting enzymes for thermotolerance, antibiotic mechanisms, and human renal metabolism to characterize drug off-target effects in silico.
Departmental Fellow, Systems Biology
Ph.D. Physics, University of Pennsylvania
B.S. Physics, Stanford University
Elizabeth is interested in how bacterial populations regulate antibiotic tolerance and the appearance of rare cells with extreme phenotypes. She is currently designing new ways to measure bacterial signaling system activity.
Ph.D. and M.S. Chemistry, MIT
B.S. Chemical Engineering, UC Berkeley
B.S. Materials Science and Engineering, UC Berkeley
Has worked in the fields of surface science, antimicrobial coatings, biomaterials, and controlled drug delivery. Now studying bacteriophages of the human gut and engineering formulations for their oral delivery.
2017 NIH F32 NRSA Postdoctoral Fellow
Ph.D. Chemical Engineering, Stanford
B.S. Chemical Engineering, University of Illinois at Urbana-Champaign
Amateur still trying to turn pro. Looking at controlling and recoding cells, after previously playing with natural product biosynthesis. Hoping to imagine again.
Ph.D. Bioengineering, Georgia Institute of Technology
S.B. Chemical Engineering, Massachusetts Institute of Technology
Tim is currently developing high throughput analyses of viral genes and their effects on intracellular signaling. In short, studying the viruses of today to better defend against the diseases of tomorrow.
Ph.D. Biophysics and Bioengineering, UC Santa Barbara
M.S. Nanoscience, Arizona State University
B.S. Biochemical Sciences, Harvard University
Dan has worked in a variety of scientific fields, including tumor angiogenesis, non-canonical amino acids, single-molecule force spectroscopy, self-assembled DNA nanostructures, and phase separation in biology. In the Silver lab, he is adding “little water bears” to this eclectic list.
Nélida R. Leiva Eriksson
Ph.D. Engineering and Biotechnology, Lund University MRC
B.S. Biochemistry and Molecular Biology, National University Federico Villarreal
Nélida is a visiting postdoc at HMS. Her research is on heme-proteins from bacteria, plants, and humans. In the Silver lab she is engineering bacterial cells to restrict their survival in human physiological conditions.
Nathan is investigating the molecular events that enable conditional behavior in biological systems. He is adding layers of requirement to proteins that function in these systems so they may only act when specific circumstances are met. Particularly, he is teaching cytokines when to pull the trigger on cell death.
B.S. in Biology and Environmental Science, Tufts University
A plant chemist escaping geology to synthetic biology, Sarabeth is fascinated by plant microbial interactions and driven to address climate change. She wants to enhance plant growth and sequester CO2 with the bionic leaf and protein microcompartments. When not biking between campuses, she can be found running, dancing, or baking crazy cakes.
M.D. Candidate, Harvard Medical School
Harvard-MIT Health Sciences and Technology (HST)
BS Mathematics, MIT
Katie may be no Doogie Howser, but she’s still full of pep about her second career as a budding physician-scientist. She would love to talk your ear off about fusion proteins, dancing and the best coffee shops to camp out in. Her enthusiasm is fueled by a diet of red bull and leftover conference room pizza.
Josh Van Zak
Josh is a Research Assistant in The Mediated Matter Group at MIT who is interested in using nature’s most overpowering adaptations to our benefit. His current research involves 3D printing bone cancer cells to generate functionally graded architectural structures that people will one day live in.
PhD candidate in Bioenergy, University of Campinas (Brazil)
BC Biotechnological Engineering, University of Sao Paulo State (Brazil)
Fernando has worked with bioprocesses and biotechnology on projects involving fermentation, purification, optimization, and scale-up. In the Silver Lab, Fernando is working with the expression of intrinsically disordered proteins in yeast.
Christine recently graduated from Harvard with a degree in Chemistry, although she never was and never intends to be a “real chemist.” She likes to put DNA places it doesn’t normally go and seeing what happens. In her free time, she enjoys painting, reality TV, and explaining jokes to people.
Juline Savigny – masters student, Ecole Normale Superieure
Jonathan Naccache – masters student, Sup’Biotech Paris
Jérôme Zürcher – undergrad, ETH Zürich
Colin Molloy – undergrad
Maya Ordonez – undergrad, University of Chicago
Julia Rogers – undergrad, Emory University
Teagan Stedman – undergrad, Harvard University
David Riglar – Assistant Professor, Imperial College London
Sasha Naydich – Consultant
Emma Spady – Postdoc
Lorena Lyon – NOVA | PBS
Disha Trivedi – Harvard University
Jernej Turnšek – Research Fellow at J. Craig Venter Institute
Isaac Plant – Engineering and Product Development at Elm Innovations
Nathalie Gruber – Graduate student, University of Applied Life Sciences Vienna
Tobias Giessen – Assistant Professor, Dept of Bioengineering, University of Michigan
Jason Lee – Harvard University
Rachel Barocio – University of California Santa Cruz
Kassandra Boada – University of Massachusetts Amherst
Andrew Verdegaal- Graduate student, Yale University
Andy Shumaker- Indigo
Florian Bieberich- Graduate student, Ruprecht Karls University Heidelberg
Yu Heng Lau- Assistant Professor, University of Sydney
Kelsey Sakimoto- KulaBio
Kira Sarup-Lytzen- Graduate Student, Novo Nordisk Foundation Center for Biosustainability in Copenhagen
Jessica Polka- Director, ASAP Bio
Connor Horton- Undergraduate, Harvard University
John Oliver- ZBiotics
Alan Pacheco- Graduate Student, Boston University
Leon Liu- Senior Data Engineer, Athenahealth
Ryan Richardson- Postdoctoral Fellow, University of Maryland
Stephanie Hays- Postdoctoral Researcher, UC Berkeley
Brendan Colón-Data Scientist, Amazon
Kriti Lall- Investment Banking
Michael Baymv- Assistant Professor, Harvard Medical School
Marta Tomaselli- Graduate Student, University of Cambridge
Una Choi- Undergraduate, Harvard University
Avi Robinson-Mosher- Scientific Programmer, DE Shaw Research
Devin Burrill- Scientist, Precision Biosciences Inc.
Matthew Robinson- Consulting
Matthew Niederhuber- Graduate Student, University of North Carolina
Cameron Myhrvold- Postdoctoral Fellow, Broad Institute of MIT/Harvard
Clovis Basier- Graduate Student, The Crick Institute
Kevin Hof- Graduate Student, École Polytechnique Fédérale de Lausanne
Michiel Karrenbelt- Institute of Systems Biology Zurich
David Lips- University of Amsterdam
Gladys Kibunyi- Charles River Lab
Johannes Bues- École Polytechnique Fédérale de Lausanne
Joost Verduijn- Ghent University
Drew MacKellar- University of Washington
Audam Chhun- PhD Candidate, University of Warwick
Thomas Perli- Delft University of Technology
Tyler J Ford- Scientist, Addgene Inc.
Matthew Mattozzi- Senior Scientist, Conagen Inc.
Wade Hicks- Head of Operations and Lab Automation, KSQ Therapeutics Inc.
Anna Chen- Life Scientist Specialist, L.E.K. Consulting
Buz Barstow- Assistant Professor of Biological Engineering, Cornell University
Wiggert Altenburg- Eindhoven University of Technology
Pia Mach- University of Tübingen
Takashi Imada- Professor, Kyoto University
Elena Schafer- Graduate student, University of Cambridge
Max Van der Ploeg – Wageningen University and Research
Michael Tscherner- Fellow, University of Vienna
Sherry Gao- Postdoc, Harvard Medical University
Nicholas Wong- Undergraduate, Harvard University
Aashna Shah- Undergraduate, Northeastern University
Ashton Omdahl- Graduate Student
Disha Trivedi- Undergraduate, Harvard University
Elizabeth Redfield- Discovery Immuno-oncology Intern